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Tau Passive Immunotherapy in Mutant P301L Mice: Antibody Affinity versus Specificity

The use of antibodies to treat neurodegenerative diseases has undergone rapid development in the past decade. To date, immunotherapeutic approaches to Alzheimer’s disease have mostly targeted amyloid beta as it is a secreted protein that can be found in plasma and CSF and is consequently accessible...

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Detalles Bibliográficos
Autores principales: d’Abramo, Cristina, Acker, Christopher M., Jimenez, Heidy T., Davies, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3639259/
https://www.ncbi.nlm.nih.gov/pubmed/23638068
http://dx.doi.org/10.1371/journal.pone.0062402