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Hypertension and Genetic Variation in Endothelial-Specific Genes

Genome-wide association (GWA) studies usually detect common genetic variants with low-to-medium effect sizes. Many contributing variants are not revealed, since they fail to reach significance after strong correction for multiple comparisons. The WTCCC study for hypertension, for example, failed to...

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Detalles Bibliográficos
Autores principales: Larsson, Erik, Wahlstrand, Björn, Hedblad, Bo, Hedner, Thomas, Kjeldsen, Sverre E., Melander, Olle, Lindahl, Per
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3639261/
https://www.ncbi.nlm.nih.gov/pubmed/23637959
http://dx.doi.org/10.1371/journal.pone.0062035