EphA2 cleavage by MT1-MMP triggers single cancer cell invasion via homotypic cell repulsion

Changes in EphA2 signaling can affect cancer cell–cell communication and motility through effects on actomyosin contractility. However, the underlying cell–surface interactions and molecular mechanisms of how EphA2 mediates these effects have remained unclear. We demonstrate here that EphA2 and memb...

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Detalles Bibliográficos
Autores principales: Sugiyama, Nami, Gucciardo, Erika, Tatti, Olga, Varjosalo, Markku, Hyytiäinen, Marko, Gstaiger, Matthias, Lehti, Kaisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3639392/
https://www.ncbi.nlm.nih.gov/pubmed/23629968
http://dx.doi.org/10.1083/jcb.201205176

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3639392/
https://www.ncbi.nlm.nih.gov/pubmed/23629968
http://dx.doi.org/10.1083/jcb.201205176

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