Cargando…
S1–S3 counter charges in the voltage sensor module of a mammalian sodium channel regulate fast inactivation
The movement of positively charged S4 segments through the electric field drives the voltage-dependent gating of ion channels. Studies of prokaryotic sodium channels provide a mechanistic view of activation facilitated by electrostatic interactions of negatively charged residues in S1 and S2 segment...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2013
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3639575/ https://www.ncbi.nlm.nih.gov/pubmed/23589580 http://dx.doi.org/10.1085/jgp.201210935 |