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Major contribution of sarcoplasmic reticulum Ca(2+) depletion during long-lasting activation of skeletal muscle
Depolarization of skeletal muscle fibers induces sarcoplasmic reticulum (SR) Ca(2+) release and contraction that progressively decline while depolarization is maintained. Voltage-dependent inactivation of SR Ca(2+) release channels and SR Ca(2+) depletion are the two processes proposed to explain th...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3639577/ https://www.ncbi.nlm.nih.gov/pubmed/23630339 http://dx.doi.org/10.1085/jgp.201310957 |