Quantitative properties and receptor reserve of the IP(3) and calcium branch of G(q)-coupled receptor signaling

G(q)-coupled plasma membrane receptors activate phospholipase C (PLC), which hydrolyzes membrane phosphatidylinositol 4,5-bisphosphate (PIP(2)) into the second messengers inositol 1,4,5-trisphosphate (IP(3)) and diacylglycerol (DAG). This leads to calcium release, protein kinase C (PKC) activation,...

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Detalles Bibliográficos
Autores principales: Dickson, Eamonn J., Falkenburger, Björn H., Hille, Bertil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3639578/
https://www.ncbi.nlm.nih.gov/pubmed/23630337
http://dx.doi.org/10.1085/jgp.201210886

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3639578/
https://www.ncbi.nlm.nih.gov/pubmed/23630337
http://dx.doi.org/10.1085/jgp.201210886

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