Exploratory Bioinformatics Study of lncRNAs in Alzheimer's Disease mRNA Sequences with Application to Drug Development

Long noncoding RNA (lncRNA) within mRNA sequences of Alzheimer's disease genes, namely, APP, APOE, PSEN1, and PSEN2, has been analyzed using fractal dimension (FD) computation and correlation analysis. We examined lncRNA by comparing mRNA FD to corresponding coding DNA sequences (CDSs) FD. APP,...

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Detalles Bibliográficos
Autores principales: Holden, T., Nguyen, A., Lin, E., Cheung, E., Dehipawala, S., Ye, J., Tremberger, G., Lieberman, D., Cheung, T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3639631/
https://www.ncbi.nlm.nih.gov/pubmed/23662159
http://dx.doi.org/10.1155/2013/579136

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3639631/
https://www.ncbi.nlm.nih.gov/pubmed/23662159
http://dx.doi.org/10.1155/2013/579136

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