Ustekinumab in chronic immune-mediated diseases: a review of long term safety and patient improvement

Ustekinumab is a fully human monoclonal antibody targeting the common p40 subunit shared by interleukin (IL)-12 and IL-23. Ustekinumab prevents the interaction of IL-12 and IL-23 with their cell surface receptors, and thus blocks T helper (Th)-1 IL-12 and Th-17 IL-23 inflammatory pathways. Ustekinum...

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Detalles Bibliográficos
Autores principales: Toussirot, Éric, Michel, Fabrice, Béreau, Matthieu, Binda, Delphine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3639711/
https://www.ncbi.nlm.nih.gov/pubmed/23641151
http://dx.doi.org/10.2147/PPA.S33162

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3639711/
https://www.ncbi.nlm.nih.gov/pubmed/23641151
http://dx.doi.org/10.2147/PPA.S33162

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