A New Class of Small Molecule Inhibitor of BMP Signaling

Growth factor signaling pathways are tightly regulated by phosphorylation and include many important kinase targets of interest for drug discovery. Small molecule inhibitors of the bone morphogenetic protein (BMP) receptor kinase ALK2 (ACVR1) are needed urgently to treat the progressively debilitati...

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Detalles Bibliográficos
Autores principales: Sanvitale, Caroline E., Kerr, Georgina, Chaikuad, Apirat, Ramel, Marie-Christine, Mohedas, Agustin H., Reichert, Sabine, Wang, You, Triffitt, James T., Cuny, Gregory D., Yu, Paul B., Hill, Caroline S., Bullock, Alex N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3639963/
https://www.ncbi.nlm.nih.gov/pubmed/23646137
http://dx.doi.org/10.1371/journal.pone.0062721

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3639963/
https://www.ncbi.nlm.nih.gov/pubmed/23646137
http://dx.doi.org/10.1371/journal.pone.0062721

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