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Effects of 5-Fluorouracil in Nuclear and Cellular Morphology, Proliferation, Cell Cycle, Apoptosis, Cytoskeletal and Caveolar Distribution in Primary Cultures of Smooth Muscle Cells

Colon cancer is one of the most prevalent types of cancer in the world and is one of the leading causes of cancer death. The anti-metabolite 5- fluorouracil (5-FU) is widely used in the treatment of patients with colon cancer and other cancer types. 5-FU-based chemotherapy has been shown to be very...

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Detalles Bibliográficos
Autores principales: Filgueiras, Marcelo de Carvalho, Morrot, Alexandre, Soares, Pedro Marcos Gomes, Costa, Manoel Luis, Mermelstein, Cláudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3639966/
https://www.ncbi.nlm.nih.gov/pubmed/23646193
http://dx.doi.org/10.1371/journal.pone.0063177