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Epistatic Interaction between BANK1 and BLK in Rheumatoid Arthritis: Results from a Large Trans-Ethnic Meta-Analysis

BACKGROUND: BANK1 and BLK belong to the pleiotropic autoimmune genes; recently, epistasis between BANK1 and BLK was detected in systemic lupus erythematosus. Although BLK has been reproducibly identified as a risk factor in rheumatoid arthritis (RA), reports are conflicting about the contribution of...

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Detalles Bibliográficos
Autores principales: Génin, Emmanuelle, Coustet, Baptiste, Allanore, Yannick, Ito, Ikue, Teruel, Maria, Constantin, Arnaud, Schaeverbeke, Thierry, Ruyssen-Witrand, Adeline, Tohma, Shigeto, Cantagrel, Alain, Vittecoq, Olivier, Barnetche, Thomas, Le Loët, Xavier, Fardellone, Patrice, Furukawa, Hiroshi, Meyer, Olivier, Fernández-Gutiérrez, Benjamin, Balsa, Alejandro, González-Gay, Miguel A., Chiocchia, Gilles, Tsuchiya, Naoyuki, Martin, Javier, Dieudé, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3639995/
https://www.ncbi.nlm.nih.gov/pubmed/23646104
http://dx.doi.org/10.1371/journal.pone.0061044