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Ablation of C/EBP Homologous Protein Does Not Protect T17M RHO Mice from Retinal Degeneration

Despite the proposed link between ablation of the CHOP protein and delay of the onset of ER stress-mediated disorders including diabetes, Alzheimer Disease, and cardiac hypertrophy, the role of CHOP protein in photoreceptor cell death associated with Autosomal Dominant Retinitis Pigmentosa (ADRP) ha...

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Detalles Bibliográficos
Autores principales: Nashine, Sonali, Bhootada, Yogesh, Lewin, Alfred S., Gorbatyuk, Marina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3640035/
https://www.ncbi.nlm.nih.gov/pubmed/23646198
http://dx.doi.org/10.1371/journal.pone.0063205