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Partial Agonism of Taurine at Gamma-Containing Native and Recombinant GABA(A) Receptors

Taurine is a semi-essential sulfonic acid found at high concentrations in plasma and mammalian tissues which regulates osmolarity, ion channel activity and glucose homeostasis. The structural requirements of GABA(A)-receptors (GABA(A)R) gated by taurine are not yet known. We determined taurine poten...

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Detalles Bibliográficos
Autores principales: Kletke, Olaf, Gisselmann, Guenter, May, Andrea, Hatt, Hanns, A. Sergeeva, Olga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3640040/
https://www.ncbi.nlm.nih.gov/pubmed/23637894
http://dx.doi.org/10.1371/journal.pone.0061733