Structural Insights into a Wildtype Domain of the Oncoprotein E6 and Its Interaction with a PDZ Domain

The high-risk human papilloma virus (HPV) oncoproteins E6 and E7 interact with key cellular regulators and are etiological agents for tumorigenesis and tumor maintenance in cervical cancer and other malignant conditions. E6 induces degradation of the tumor suppressor p53, activates telomerase and de...

Descripción completa

Detalles Bibliográficos
Autores principales: Mischo, André, Ohlenschläger, Oliver, Hortschansky, Peter, Ramachandran, Ramadurai, Görlach, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3640046/
https://www.ncbi.nlm.nih.gov/pubmed/23638119
http://dx.doi.org/10.1371/journal.pone.0062584

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3640046/
https://www.ncbi.nlm.nih.gov/pubmed/23638119
http://dx.doi.org/10.1371/journal.pone.0062584

Ejemplares similares