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Effects of In Vitro Low Oxygen Tension Preconditioning of Adipose Stromal Cells on Their In Vivo Chondrogenic Potential: Application in Cartilage Tissue Repair

PURPOSE: Multipotent stromal cell (MSC)-based regenerative strategy has shown promise for the repair of cartilage, an avascular tissue in which cells experience hypoxia. Hypoxia is known to promote the early chondrogenic differentiation of MSC. The aim of our study was therefore to determine whether...

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Detalles Bibliográficos
Autores principales: Portron, Sophie, Merceron, Christophe, Gauthier, Olivier, Lesoeur, Julie, Sourice, Sophie, Masson, Martial, Fellah, Borhane Hakim, Geffroy, Olivier, Lallemand, Elodie, Weiss, Pierre, Guicheux, Jérôme, Vinatier, Claire
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3640047/
https://www.ncbi.nlm.nih.gov/pubmed/23638053
http://dx.doi.org/10.1371/journal.pone.0062368