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Hepatitis C Virus NS2 Protein Inhibits DNA Damage Pathway by Sequestering p53 to the Cytoplasm

Chronic hepatitis C virus (HCV) infection is an important cause of morbidity and mortality globally, and often leads to end-stage liver disease. The DNA damage checkpoint pathway induces cell cycle arrest for repairing DNA in response to DNA damage. HCV infection has been involved in this pathway. I...

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Detalles Bibliográficos
Autores principales: Bittar, Cintia, Shrivastava, Shubham, Bhanja Chowdhury, Joydip, Rahal, Paula, Ray, Ratna B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3640050/
https://www.ncbi.nlm.nih.gov/pubmed/23638118
http://dx.doi.org/10.1371/journal.pone.0062581