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Hepatitis C Virus NS2 Protein Inhibits DNA Damage Pathway by Sequestering p53 to the Cytoplasm
Chronic hepatitis C virus (HCV) infection is an important cause of morbidity and mortality globally, and often leads to end-stage liver disease. The DNA damage checkpoint pathway induces cell cycle arrest for repairing DNA in response to DNA damage. HCV infection has been involved in this pathway. I...
Autores principales: | Bittar, Cintia, Shrivastava, Shubham, Bhanja Chowdhury, Joydip, Rahal, Paula, Ray, Ratna B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3640050/ https://www.ncbi.nlm.nih.gov/pubmed/23638118 http://dx.doi.org/10.1371/journal.pone.0062581 |
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