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VPPIPP and IPPVPP: Two Hexapeptides Innovated to Exert Antihypertensive Activity

In this study, two hexapeptides of IPPVPP and VPPIPP were innovated by using two commercial antihypertensive peptides IPP and VPP as two domains cis-linked and trans-linked, respectively. The IPPVPP and VPPIPP were chemically synthesized and evaluated for the antihypertensive activity in vitro/vivo....

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Detalles Bibliográficos
Autores principales: Ding, Fengyun, Qian, Bingjun, Zhao, Xin, Shen, Shanqi, Deng, Yun, Wang, Danfeng, Zhang, Feng, Sui, Zhongquan, Jing, Pu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3640069/
https://www.ncbi.nlm.nih.gov/pubmed/23638059
http://dx.doi.org/10.1371/journal.pone.0062384