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Age-Mediated Transcriptomic Changes in Adult Mouse Substantia Nigra

Substantia nigra pars compacta (SNpc) is highly sensitive to normal aging and selectively degenerates in Parkinson's disease (PD). Until now, molecular mechanisms behind SNpc aging have not been fully investigated using high throughput techniques. Here, we show early signs of aging in SNpc, whi...

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Detalles Bibliográficos
Autores principales: Gao, Lin, Hidalgo-Figueroa, María, Escudero, Luis M., Díaz-Martín, Juan, López-Barneo, José, Pascual, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3640071/
https://www.ncbi.nlm.nih.gov/pubmed/23638090
http://dx.doi.org/10.1371/journal.pone.0062456