Sub-Sets of Cancer Stem Cells Differ Intrinsically in Their Patterns of Oxygen Metabolism

The glycolytic response of hypoxic cells is primarily mediated by the hypoxia inducible factor alpha (HIF-1α) but even in the presence of abundant oxygen tumours typically show high rates of glycolysis. Higher levels of HIF-1α in tumours are associated with a poorer prognosis and up-regulation of ma...

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Detalles Bibliográficos
Autores principales: Gammon, Luke, Biddle, Adrian, Heywood, Hannah K., Johannessen, Anne C., Mackenzie, Ian C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3640080/
https://www.ncbi.nlm.nih.gov/pubmed/23638097
http://dx.doi.org/10.1371/journal.pone.0062493

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3640080/
https://www.ncbi.nlm.nih.gov/pubmed/23638097
http://dx.doi.org/10.1371/journal.pone.0062493

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