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Sialic acids acquired by Pseudomonas aeruginosa are involved in reduced complement deposition and siglec mediated host-cell recognition

The opportunism of Pseudomonas aeruginosa (PA) in immunocompromised hosts prompted us to explore the potential role of sialic acids (Sia) in this phenomenon. Culture of PA in the presence of exogenous Sia resulted in linkage-specific incorporation of Sia which was associated with decreased complemen...

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Detalles Bibliográficos
Autores principales: Khatua, Biswajit, Ghoshal, Angana, Bhattacharya, Kaushik, Mandal, Chandan, Saha, Bibhuti, Crocker, Paul R., Mandal, Chitra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science B.V 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3640159/
https://www.ncbi.nlm.nih.gov/pubmed/19945458
http://dx.doi.org/10.1016/j.febslet.2009.11.087