Synthesis, DNA Binding and Antitumor Evaluation of Styelsamine and Cystodytin Analogues

A series of N-14 sidechain substituted analogues of styelsamine (pyrido[4,3,2-mn]acridine) and cystodytin (pyrido[4,3,2-mn]acridin-4-one) alkaloids have been prepared and evaluated for their DNA binding affinity and antiproliferative activity towards a panel of human tumor cell lines. Overall it was...

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Detalles Bibliográficos
Autores principales: Fong, Hugo K. H., Copp, Brent R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3640380/
https://www.ncbi.nlm.nih.gov/pubmed/23358307
http://dx.doi.org/10.3390/md11020274

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3640380/
https://www.ncbi.nlm.nih.gov/pubmed/23358307
http://dx.doi.org/10.3390/md11020274

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