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Synthesis, DNA Binding and Antitumor Evaluation of Styelsamine and Cystodytin Analogues
A series of N-14 sidechain substituted analogues of styelsamine (pyrido[4,3,2-mn]acridine) and cystodytin (pyrido[4,3,2-mn]acridin-4-one) alkaloids have been prepared and evaluated for their DNA binding affinity and antiproliferative activity towards a panel of human tumor cell lines. Overall it was...
Autores principales: | Fong, Hugo K. H., Copp, Brent R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3640380/ https://www.ncbi.nlm.nih.gov/pubmed/23358307 http://dx.doi.org/10.3390/md11020274 |
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