Construction of Monophosphoryl Lipid A Producing Escherichia coli Mutants and Comparison of Immuno-Stimulatory Activities of Their Lipopolysaccharides

The lipid A moiety of Escherichia coli lipopolysaccharide is a hexaacylated disaccharide of glucosamine phosphorylated at the 1- and 4′-positions. It can be recognized by the TLR4/MD-2 complex of mammalian immune cells, leading to release of proinflammatory cytokines. The toxicity of lipid A depends...

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Detalles Bibliográficos
Autores principales: Han, Yaning, Li, Ye, Chen, Jiuzhou, Tan, Yanzhen, Guan, Feng, Wang, Xiaoyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3640385/
https://www.ncbi.nlm.nih.gov/pubmed/23434832
http://dx.doi.org/10.3390/md11020363

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3640385/
https://www.ncbi.nlm.nih.gov/pubmed/23434832
http://dx.doi.org/10.3390/md11020363

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