Cytotoxic Effect of Clerosterol Isolated from Codium fragile on A2058 Human Melanoma Cells

The cytotoxic effects and mechanism of action of clerosterol, isolated from the marine alga Codium fragile, were investigated in A2058 human melanoma cells. Clerosterol inhibited the growth of A2058 cells with an IC(50) of 150 µM and induced apoptotic cell death, as evidenced by DNA fragmentation, a...

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Detalles Bibliográficos
Autores principales: Kim, Areum Daseul, Lee, Youngki, Kang, Sang-Hyuck, Kim, Gi Young, Kim, Hye Sun, Hyun, Jin Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3640389/
https://www.ncbi.nlm.nih.gov/pubmed/23389088
http://dx.doi.org/10.3390/md11020418

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3640389/
https://www.ncbi.nlm.nih.gov/pubmed/23389088
http://dx.doi.org/10.3390/md11020418

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