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HIV-1 Diversity in the Envelope Glycoproteins: Implications for Viral Entry Inhibition

Entry of HIV-1 into a host cell is a multi-step process, with the viral envelope gp120 and gp41 acting sequentially to mediate the viral attachment, CD4 binding, coreceptor binding, and fusion of the viral and host membranes. The emerging class of antiretroviral agents, collectively known as entry i...

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Detalles Bibliográficos
Autores principales: Araújo, Leonardo Augusto Luvison, Almeida, Sabrina E. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3640516/
https://www.ncbi.nlm.nih.gov/pubmed/23389465
http://dx.doi.org/10.3390/v5020595