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Low Copper and High Manganese Levels in Prion Protein Plaques

Accumulation of aggregates rich in an abnormally folded form of the prion protein characterize the neurodegeneration caused by transmissible spongiform encephalopathies (TSEs). The molecular triggers of plaque formation and neurodegeneration remain unknown, but analyses of TSE-infected brain homogen...

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Detalles Bibliográficos
Autores principales: Johnson, Christopher J., Gilbert, P.U.P.A., Abrecht, Mike, Baldwin, Katherine L., Russell, Robin E., Pedersen, Joel A., Aiken, Judd M., McKenzie, Debbie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3640519/
https://www.ncbi.nlm.nih.gov/pubmed/23435237
http://dx.doi.org/10.3390/v5020654