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Low Copper and High Manganese Levels in Prion Protein Plaques
Accumulation of aggregates rich in an abnormally folded form of the prion protein characterize the neurodegeneration caused by transmissible spongiform encephalopathies (TSEs). The molecular triggers of plaque formation and neurodegeneration remain unknown, but analyses of TSE-infected brain homogen...
Autores principales: | Johnson, Christopher J., Gilbert, P.U.P.A., Abrecht, Mike, Baldwin, Katherine L., Russell, Robin E., Pedersen, Joel A., Aiken, Judd M., McKenzie, Debbie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3640519/ https://www.ncbi.nlm.nih.gov/pubmed/23435237 http://dx.doi.org/10.3390/v5020654 |
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