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Venom Peptides as a Rich Source of Ca(v)2.2 Channel Blockers

Ca(v)2.2 is a calcium channel subtype localized at nerve terminals, including nociceptive fibers, where it initiates neurotransmitter release. Ca(v)2.2 is an important contributor to synaptic transmission in ascending pain pathways, and is up-regulated in the spinal cord in chronic pain states along...

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Detalles Bibliográficos
Autores principales: Sousa, Silmara R., Vetter, Irina, Lewis, Richard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3640536/
https://www.ncbi.nlm.nih.gov/pubmed/23381143
http://dx.doi.org/10.3390/toxins5020286