Cargando…
Venom Peptides as a Rich Source of Ca(v)2.2 Channel Blockers
Ca(v)2.2 is a calcium channel subtype localized at nerve terminals, including nociceptive fibers, where it initiates neurotransmitter release. Ca(v)2.2 is an important contributor to synaptic transmission in ascending pain pathways, and is up-regulated in the spinal cord in chronic pain states along...
Autores principales: | Sousa, Silmara R., Vetter, Irina, Lewis, Richard J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3640536/ https://www.ncbi.nlm.nih.gov/pubmed/23381143 http://dx.doi.org/10.3390/toxins5020286 |
Ejemplares similares
-
Expression and Pharmacology of Endogenous Ca(v) Channels in SH-SY5Y Human Neuroblastoma Cells
por: Sousa, Silmara R., et al.
Publicado: (2013) -
Addition of K22 Converts Spider Venom Peptide Pme2a from an Activator to an Inhibitor of Na(V)1.7
por: Yin, Kathleen, et al.
Publicado: (2020) -
ω-Conotoxin GVIA Mimetics that Bind and Inhibit Neuronal Ca(v)2.2 Ion Channels
por: Tranberg, Charlotte Elisabet, et al.
Publicado: (2012) -
Antifungal Effect of Chitosan as Ca(2+) Channel Blocker
por: Lee, Choon Geun, et al.
Publicado: (2016) -
Molecular Simulations of Disulfide-Rich Venom Peptides with Ion Channels and Membranes
por: Deplazes, Evelyne
Publicado: (2017)