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Opioids and clonidine modulate cytokine production and opioid receptor expression in neonatal immune cells

OBJECTIVE: Opioids and clonidine, used in for sedation, analgesia and control of opioid withdrawal in neonates, directly or indirectly activate opioid receptors expressed in immune cells. Therefore, our objective is to study how clinically relevant concentrations of different opioids and clonidine c...

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Detalles Bibliográficos
Autores principales: Chavez-Valdez, Raul, Kovell, Lara, Ahlawat, Rajni, McLemore, Gabrielle L., Wills-Karp, Marsha, Gauda, Estelle B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3640758/
https://www.ncbi.nlm.nih.gov/pubmed/23047422
http://dx.doi.org/10.1038/jp.2012.124