The Fun30 ATP-dependent nucleosome remodeler promotes resection of DNA double-strand break ends

Chromosomal double-strand breaks (DSBs) are resected by 5′-nucleases to form 3′ single-strand DNA (ssDNA) substrates for binding by homologous recombination and DNA damage checkpoint proteins. Two redundant pathways of extensive resection were described both in cells (1-3) and in vitro (4-6), one re...

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Detalles Bibliográficos
Autores principales: Chen, Xuefeng, Cui, Dandan, Papusha, Alma, Zhang, Xiaotian, Chu, Chia-Dwo, Tang, Jiangwu, Chen, Kaifu, Pan, Xuewen, Ira, Grzegorz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3640768/
https://www.ncbi.nlm.nih.gov/pubmed/22960743
http://dx.doi.org/10.1038/nature11355

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3640768/
https://www.ncbi.nlm.nih.gov/pubmed/22960743
http://dx.doi.org/10.1038/nature11355

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