Design, Mechanism of Action, Bioavailability and Therapeutic Effects of Mn Porphyrin-Based Redox Modulators

Based on aqueous redox chemistry and simple in vivo models of oxidative stress, Escherichia coli and Saccharomyces cerevisiae, the cationic Mn(III) N-substituted pyridylporphyrins (MnPs) have been identified as the most potent cellular redox modulators within the porphyrin class of drugs; their effi...

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Detalles Bibliográficos
Autores principales: Tovmasyan, Artak, Sheng, Huaxin, Weitner, Tin, Arulpragasam, Amanda, Lu, Miaomiao, Warner, David S., Vujaskovic, Zeljko, Spasojevic, Ivan, Batinic-Haberle, Ines
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2013
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3640855/
https://www.ncbi.nlm.nih.gov/pubmed/23075911
http://dx.doi.org/10.1159/000341715

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3640855/
https://www.ncbi.nlm.nih.gov/pubmed/23075911
http://dx.doi.org/10.1159/000341715

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