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Design, Mechanism of Action, Bioavailability and Therapeutic Effects of Mn Porphyrin-Based Redox Modulators
Based on aqueous redox chemistry and simple in vivo models of oxidative stress, Escherichia coli and Saccharomyces cerevisiae, the cationic Mn(III) N-substituted pyridylporphyrins (MnPs) have been identified as the most potent cellular redox modulators within the porphyrin class of drugs; their effi...
Autores principales: | Tovmasyan, Artak, Sheng, Huaxin, Weitner, Tin, Arulpragasam, Amanda, Lu, Miaomiao, Warner, David S., Vujaskovic, Zeljko, Spasojevic, Ivan, Batinic-Haberle, Ines |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
S. Karger AG
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3640855/ https://www.ncbi.nlm.nih.gov/pubmed/23075911 http://dx.doi.org/10.1159/000341715 |
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