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Transcriptional analysis of the three Nlrp1 paralogs in mice

BACKGROUND: Signals of danger and damage in the cytosol of cells are sensed by NOD-like receptors (NLRs), which are components of multiprotein complexes called inflammasomes. Inflammasomes activate caspase-1, resulting in IL-1-beta and IL-18 secretion and an inflammatory response. To date, the only...

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Detalles Bibliográficos
Autores principales: Sastalla, Inka, Crown, Devorah, Masters, Seth L, McKenzie, Andrew, Leppla, Stephen H, Moayeri, Mahtab
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3641005/
https://www.ncbi.nlm.nih.gov/pubmed/23506131
http://dx.doi.org/10.1186/1471-2164-14-188