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A Site-Specific Recombinase-Based Method to Produce Antibiotic Selectable Marker Free Transgenic Cattle

Antibiotic selectable marker genes have been widely used to generate transgenic animals. Once transgenic animals have been obtained, the selectable marker is no longer necessary but raises public concerns regarding biological safety. The aim of this study was to prepare competent antibiotic selectab...

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Detalles Bibliográficos
Autores principales: Yu, Yuan, Wang, Yongsheng, Tong, Qi, Liu, Xu, Su, Feng, Quan, Fusheng, Guo, Zekun, Zhang, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3641042/
https://www.ncbi.nlm.nih.gov/pubmed/23658729
http://dx.doi.org/10.1371/journal.pone.0062457