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Mutations Disrupting Histone Methylation Have Different Effects on Replication Timing in S. pombe Centromere

The fission yeast pericentromere comprises repetitive sequence elements packaged into heterchromatin marked by histone H3K9 methylation and Swi6 binding. Transient disruption of Swi6 during S phase allows a period of RNA synthesis which programs the RNAi machinery to maintain histone methylation. Ho...

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Detalles Bibliográficos
Autores principales: Li, Pao-Chen, Green, Marc D., Forsburg, Susan L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3641051/
https://www.ncbi.nlm.nih.gov/pubmed/23658693
http://dx.doi.org/10.1371/journal.pone.0061464