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Critical Role of a Survivin/TGF-β/mTORC1 Axis in IGF-I-Mediated Growth of Prostate Epithelial Cells

Survivin is a unique member of the inhibitor of apoptosis (IAP) proteins that is overexpressed in numerous cancers through poorly defined mechanisms. One such mechanism may be through constitutive activation of the insulin-like growth factor-I (IGF-I) signaling pathway, implicated in the development...

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Detalles Bibliográficos
Autores principales: Song, Kyung, Shankar, Eswar, Yang, Jiayi, Bane, Kara L., Wahdan-Alaswad, Reema, Danielpour, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3641055/
https://www.ncbi.nlm.nih.gov/pubmed/23658701
http://dx.doi.org/10.1371/journal.pone.0061896