Cargando…

A Subdomain Interaction at the Base of the Lever Allosterically Tunes the Mechanochemical Mechanism of Myosin 5a

The motor domain of myosin is the core element performing mechanochemical energy transduction. This domain contains the actin and ATP binding sites and the base of the force-transducing lever. Coordinated subdomain movements within the motor are essential in linking the ATPase chemical cycle to tran...

Descripción completa

Detalles Bibliográficos
Autores principales: Nagy, Nikolett T., Chakraborty, Saikat, Harami, Gábor M., Sellers, James R., Sakamoto, Takeshi, Kovács, Mihály
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3641075/
https://www.ncbi.nlm.nih.gov/pubmed/23650521
http://dx.doi.org/10.1371/journal.pone.0062640