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A Subdomain Interaction at the Base of the Lever Allosterically Tunes the Mechanochemical Mechanism of Myosin 5a
The motor domain of myosin is the core element performing mechanochemical energy transduction. This domain contains the actin and ATP binding sites and the base of the force-transducing lever. Coordinated subdomain movements within the motor are essential in linking the ATPase chemical cycle to tran...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3641075/ https://www.ncbi.nlm.nih.gov/pubmed/23650521 http://dx.doi.org/10.1371/journal.pone.0062640 |