Cargando…
A Subdomain Interaction at the Base of the Lever Allosterically Tunes the Mechanochemical Mechanism of Myosin 5a
The motor domain of myosin is the core element performing mechanochemical energy transduction. This domain contains the actin and ATP binding sites and the base of the force-transducing lever. Coordinated subdomain movements within the motor are essential in linking the ATPase chemical cycle to tran...
Autores principales: | Nagy, Nikolett T., Chakraborty, Saikat, Harami, Gábor M., Sellers, James R., Sakamoto, Takeshi, Kovács, Mihály |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3641075/ https://www.ncbi.nlm.nih.gov/pubmed/23650521 http://dx.doi.org/10.1371/journal.pone.0062640 |
Ejemplares similares
-
The HRDC domain of E. coli RecQ helicase controls single-stranded DNA translocation and double-stranded DNA unwinding rates without affecting mechanoenzymatic coupling
por: Harami, Gábor M., et al.
Publicado: (2015) -
Myosin and Tropomyosin Stabilize the Conformation of Formin-nucleated Actin Filaments
por: Ujfalusi, Zoltán, et al.
Publicado: (2012) -
Functional fine-tuning between bacterial DNA recombination initiation and quality control systems
por: Ferencziová, Veronika, et al.
Publicado: (2018) -
Effect of allosteric inhibition of non-muscle myosin 2 on its intracellular diffusion
por: Horváth, Ádám I., et al.
Publicado: (2020) -
Different degrees of lever arm rotation control myosin step size
por: Köhler, Danny, et al.
Publicado: (2003)