Cargando…
Human RECQ1 Interacts with Ku70/80 and Modulates DNA End-Joining of Double-Strand Breaks
Genomic instability is a known precursor to cancer and aging. The RecQ helicases are a highly conserved family of DNA-unwinding enzymes that play key roles in maintaining genome stability in all living organisms. Human RecQ homologs include RECQ1, BLM, WRN, RECQ4, and RECQ5β, three of which have bee...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3641083/ https://www.ncbi.nlm.nih.gov/pubmed/23650516 http://dx.doi.org/10.1371/journal.pone.0062481 |