Cargando…

Human RECQ1 Interacts with Ku70/80 and Modulates DNA End-Joining of Double-Strand Breaks

Genomic instability is a known precursor to cancer and aging. The RecQ helicases are a highly conserved family of DNA-unwinding enzymes that play key roles in maintaining genome stability in all living organisms. Human RecQ homologs include RECQ1, BLM, WRN, RECQ4, and RECQ5β, three of which have bee...

Descripción completa

Detalles Bibliográficos
Autores principales:	Parvathaneni, Swetha, Stortchevoi, Alexei, Sommers, Joshua A., Brosh, Robert M., Sharma, Sudha
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3641083/ https://www.ncbi.nlm.nih.gov/pubmed/23650516 http://dx.doi.org/10.1371/journal.pone.0062481

Ejemplares similares

PARP regulates nonhomologous end joining through retention of Ku at double-strand breaks
por: Couto, C. Anne-Marie, et al.
Publicado: (2011)

The end-joining factor Ku acts in the end-resection of double strand break-free arrested replication forks
por: Teixeira-Silva, Ana, et al.
Publicado: (2017)

Distinct roles of XRCC4 and Ku80 in non-homologous end-joining of endonuclease- and ionizing radiation-induced DNA double-strand breaks
por: Schulte-Uentrop, Leonie, et al.
Publicado: (2008)

Ku80 removal from DNA through double strand break–induced ubiquitylation
por: Postow, Lisa, et al.
Publicado: (2008)

Ku Regulates the Non-Homologous End Joining Pathway Choice of DNA Double-Strand Break Repair in Human Somatic Cells
por: Fattah, Farjana, et al.
Publicado: (2010)

PARP retains Ku at double-strand breaks
por: Short, Ben
Publicado: (2011)

Characterization of Double-Strand Break Repair Protein Ku80 Location Within the Murine Retina
por: Müller, Brigitte, et al.
Publicado: (2022)

Human RecQ Helicases in DNA Double-Strand Break Repair
por: Lu, Huiming, et al.
Publicado: (2021)

Genetic polymorphisms of DNA double strand break gene Ku70 and gastric cancer in Taiwan
por: Yang, Mei-Due, et al.
Publicado: (2011)

Coordinated nuclease activities counteract Ku at single-ended DNA double-strand breaks
por: Chanut, Pauline, et al.
Publicado: (2016)

The Multifaceted Roles of Ku70/80
por: Zahid, Sayma, et al.
Publicado: (2021)

C-Terminal Extensions of Ku70 and Ku80 Differentially Influence DNA End Binding Properties
por: Inagawa, Takabumi, et al.
Publicado: (2020)

Repair of double-strand breaks by nonhomologous end joining in the absence of Mre11
por: Di Virgilio, Michela, et al.
Publicado: (2005)

Smarcal1 promotes double-strand-break repair by nonhomologous end-joining
por: Keka, Islam Shamima, et al.
Publicado: (2015)

Corrigendum: Coordinated nuclease activities counteract Ku at single-ended DNA double-strand breaks
por: Chanut, Pauline, et al.
Publicado: (2017)

Mismatch-repair protein MSH6 is associated with Ku70 and regulates DNA double-strand break repair
por: Shahi, Ankita, et al.
Publicado: (2011)

DNA double-strand break induction in Ku80-deficient CHO cells following Boron Neutron Capture Reaction
por: Kinashi, Yuko, et al.
Publicado: (2011)

To Join or Not to Join: Decision Points Along the Pathway to Double-Strand Break Repair vs. Chromosome End Protection
por: Ackerson, Stephanie M., et al.
Publicado: (2021)

Human RECQ5 helicase promotes repair of DNA double-strand breaks by synthesis-dependent strand annealing
por: Paliwal, Shreya, et al.
Publicado: (2014)

Subdiffusion Supports Joining Of Correct Ends During Repair Of DNA Double-Strand Breaks
por: Girst, S., et al.
Publicado: (2013)

ZEB1 promotes non-homologous end joining double-strand break repair
por: Genetta, Thomas L, et al.
Publicado: (2023)

Evidence for Ku70/Ku80 association with full-length RAG1
por: Raval, Prafulla, et al.
Publicado: (2008)

WASH interacts with Ku to regulate DNA double-stranded break repair
por: Wang, Tao, et al.
Publicado: (2021)

PAXX promotes KU accumulation at DNA breaks and is essential for end-joining in XLF-deficient mice
por: Liu, Xiangyu, et al.
Publicado: (2017)

Bridging of double-stranded breaks by the nonhomologous end-joining ligation complex is modulated by DNA end chemistry
por: Reid, Dylan A., et al.
Publicado: (2017)

EAF2 regulates DNA repair through Ku70/Ku80 in the prostate
por: Ai, J, et al.
Publicado: (2017)

Essential Factors for Incompatible DNA End Joining at Chromosomal DNA Double Strand Breaks In Vivo
por: Ogiwara, Hideaki, et al.
Publicado: (2011)

Processing of DNA double strand breaks by alternative non-homologous end-joining in hyperacetylated chromatin
por: Manova, Vasilissa, et al.
Publicado: (2012)

Assays for DNA double-strand break repair by microhomology-based end-joining repair mechanisms
por: Kostyrko, Kaja, et al.
Publicado: (2016)

Plant organellar DNA polymerases repair double-stranded breaks by microhomology-mediated end-joining
por: García-Medel, Paola L, et al.
Publicado: (2019)

CCAR2 functions downstream of the Shieldin complex to promote double-strand break end-joining
por: Iyer, Divya Ramalingam, et al.
Publicado: (2022)

RECQ1 expression is upregulated in response to DNA damage and in a p53-dependent manner
por: Parvathaneni, Swetha, et al.
Publicado: (2017)

Ku80 attentuates cytotoxicity induced by green fluorescent protein transduction independently of non-homologous end joining()
por: Koike, Manabu, et al.
Publicado: (2012)

Hierarchy of nonhomologous end-joining, single-strand annealing and gene conversion at site-directed DNA double-strand breaks
por: Mansour, Wael Y., et al.
Publicado: (2008)

Molecular characterization of KU70 and KU80 homologues and exploitation of a KU70-deficient mutant for improving gene deletion frequency in Rhodosporidium toruloides
por: Koh, Chong Mei John, et al.
Publicado: (2014)

XAB2 promotes Ku eviction from single-ended DNA double-strand breaks independently of the ATM kinase
por: Sharma, Abhishek Bharadwaj, et al.
Publicado: (2021)

Replication stress induces specific enrichment of RECQ1 at common fragile sites FRA3B and FRA16D
por: Lu, Xing, et al.
Publicado: (2013)

Alternative end-joining catalyzes class switch recombination in the absence of both Ku70 and DNA ligase 4
por: Boboila, Cristian, et al.
Publicado: (2010)

Alternative end-joining catalyzes class switch recombination in the absence of both Ku70 and DNA ligase 4
por: Boboila, Cristian, et al.
Publicado: (2013)

Inhibition of double-strand break non-homologous end-joining by cisplatin adducts in human cell extracts
por: Diggle, C. P., et al.
Publicado: (2005)

Cannot write session to /tmp/vufind_sessions/sess_arh6hj6oht6h3oofeojhfe8l9l