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In Vivo “MRI Phenotyping” Reveals Changes in Extracellular Matrix Transport and Vascularization That Mediate VEGF-Driven Increase in Breast Cancer Metastasis

PURPOSE: To gain new insights into the relationship between angiogenic factors in breast cancer and their effect on extracellular matrix (ECM) remodeling and metastasis, we characterized and validated the “metastatic signature” of human breast cancer cell lines engineered to overexpress VEGF in term...

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Detalles Bibliográficos
Autores principales: Pathak, Arvind P., McNutt, Stephen, Shah, Tariq, Wildes, Flonne, Raman, Venu, Bhujwalla, Zaver M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3641100/
https://www.ncbi.nlm.nih.gov/pubmed/23650550
http://dx.doi.org/10.1371/journal.pone.0063146