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In Vivo “MRI Phenotyping” Reveals Changes in Extracellular Matrix Transport and Vascularization That Mediate VEGF-Driven Increase in Breast Cancer Metastasis
PURPOSE: To gain new insights into the relationship between angiogenic factors in breast cancer and their effect on extracellular matrix (ECM) remodeling and metastasis, we characterized and validated the “metastatic signature” of human breast cancer cell lines engineered to overexpress VEGF in term...
Autores principales: | Pathak, Arvind P., McNutt, Stephen, Shah, Tariq, Wildes, Flonne, Raman, Venu, Bhujwalla, Zaver M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3641100/ https://www.ncbi.nlm.nih.gov/pubmed/23650550 http://dx.doi.org/10.1371/journal.pone.0063146 |
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