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Association of the Protein-Tyrosine Phosphatase DEP-1 with Its Substrate FLT3 Visualized by In Situ Proximity Ligation Assay

Protein-tyrosine phosphatases (PTPs) are important regulators of signal transduction processes. Essential for the functional characterization of PTPs is the identification of their physiological substrates, and an important step towards this goal is the demonstration of a physical interaction. The a...

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Detalles Bibliográficos
Autores principales: Böhmer, Sylvia-Annette, Weibrecht, Irene, Söderberg, Ola, Böhmer, Frank-D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3641115/
https://www.ncbi.nlm.nih.gov/pubmed/23650535
http://dx.doi.org/10.1371/journal.pone.0062871