Overexpression of Retinal Degeneration Slow (RDS) Protein Adversely Affects Rods in the rd7 Model of Enhanced S-Cone Syndrome

The nuclear receptor NR2E3 promotes expression of rod photoreceptor genes while repressing cone genes. Mice lacking NR2E3 (Nr2e3(rd7/rd7) referred to here as rd7) are a model for enhanced S-cone syndrome, a disease associated with increased sensitivity to blue light and night blindness. Rd7 retinas...

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Detalles Bibliográficos
Autores principales: Chakraborty, Dibyendu, Conley, Shannon M., Naash, Muna I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3641132/
https://www.ncbi.nlm.nih.gov/pubmed/23650562
http://dx.doi.org/10.1371/journal.pone.0063321

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3641132/
https://www.ncbi.nlm.nih.gov/pubmed/23650562
http://dx.doi.org/10.1371/journal.pone.0063321

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