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Calnexin-Assisted Biogenesis of the Neuronal Glycine Transporter 2 (GlyT2)

The neuronal transporter GlyT2 is a polytopic, 12-transmembrane domain, plasma membrane glycoprotein involved in the removal and recycling of synaptic glycine from inhibitory synapses. Mutations in the human GlyT2 gene (SLC6A5) that cause deficient glycine transport or defective GlyT2 trafficking ar...

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Detalles Bibliográficos
Autores principales: Arribas-González, Esther, Alonso-Torres, Pablo, Aragón, Carmen, López-Corcuera, Beatriz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3641136/
https://www.ncbi.nlm.nih.gov/pubmed/23650557
http://dx.doi.org/10.1371/journal.pone.0063230