BNIP3 acts as transcriptional repressor of death receptor-5 expression and prevents TRAIL-induced cell death in gliomas

Glioblastoma multiforme (GBM) is the most common and malignant brain tumor, and current treatment modalities such as surgical resection, adjuvant radiotherapy and temozolomide (TMZ) chemotherapy are ineffective. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is a novel cancer therap...

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Detalles Bibliográficos
Autores principales: Burton, T R, Henson, E S, Azad, M B, Brown, M, Eisenstat, D D, Gibson, S B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3641324/
https://www.ncbi.nlm.nih.gov/pubmed/23579274
http://dx.doi.org/10.1038/cddis.2013.100

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3641324/
https://www.ncbi.nlm.nih.gov/pubmed/23579274
http://dx.doi.org/10.1038/cddis.2013.100

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