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BNIP3 acts as transcriptional repressor of death receptor-5 expression and prevents TRAIL-induced cell death in gliomas
Glioblastoma multiforme (GBM) is the most common and malignant brain tumor, and current treatment modalities such as surgical resection, adjuvant radiotherapy and temozolomide (TMZ) chemotherapy are ineffective. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is a novel cancer therap...
Autores principales: | Burton, T R, Henson, E S, Azad, M B, Brown, M, Eisenstat, D D, Gibson, S B |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3641324/ https://www.ncbi.nlm.nih.gov/pubmed/23579274 http://dx.doi.org/10.1038/cddis.2013.100 |
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